Prostagladin

what is the relationship between NSAIDs and Prostagladin (eicosanoids) ?

http://en.wikipedia.org/wiki/Eicosanoid
NSAID is a drug that block COX1 enzyme that convert Arachidonic Acid to Prostaglandin.
Prostaglandin Function:
- PGD2:Promotion of sleep
-PGE2: +Smooth muscle contraction;
             +inducing pain, heat, fever;
             +bronchoconstriction
-PGF2α:Uterine contraction
-PGI2: +Inhibition of platelet aggregation;
           + vasodilation; embryo implantation
http://en.wikipedia.org/wiki/Eicosanoid#Function_and_pharmacology