Thursday, September 2, 2010

cAMP-dependent pathway, ASA the adenylyl cyclase pathway Mechanism

Mechanism of cAMP-dependent signaling. In this figure, the neurotransmitter epinephrine (adrenaline) and its receptor (pink) is used as an example. The activated receptor releases the Gs alpha protein (tan) from the beta amd gamma subunits (blue and green) in the heterotrimeric G-protein complex. The activated Gs alpha protein in turn activates adenylyl cyclase (purple), which converts ATP into the second messenger cAMP

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